Peripheral Red Blood Cells in Covid-19 Patients: Morphology | Abstract
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Annals of Experimental Biology


Peripheral Red Blood Cells in Covid-19 Patients: Morphology

Author(s): Peter Smith*

The Covid-19 pandemic has caused a global health disaster and made it extremely difficult to find effective ways to limit the disease. The disease’s pathophysiology is still changing. The peripheral blood picture in patients with Covid-19 has not received much study in the quest to understand the etiology of the virus. This investigation has concentrated on the Geimsa-stained morphology of red blood cells. The findings revealed unique morphological modifications in RBCs, such as rouleauxformation. In 98.3% of the patients, it was found that the RBCs had ringlike stained bodies. None of the control smears contained any of these ring bodies. On the cell walls of the RBCs in some smears, stained particles could be detected. RBCs in the shape of tears and macrocytosis with central polar stomatocytes were seen. There have been reports of neutrophil nuclei with fetus-like organization, anisocytosis, and moderate poikilocytosis. Reticulocyte and platelet counts are low relative to controls in covid-19 patients. Blood smears from each patient revealed significant lymphocytopenia, thrombocytopenia, and a mild neutrophilia with fetus-like nuclei.