Scholars Research Library

Scholars Research Library

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An efficient synthesis of 1, 2, 4-triazine derivatives and their in vitro antimicrobial activity

Author(s): Bhaskar S. Dawane, Shuddhodan N.Kadam, Baseer M.Shaikh

A simple and efficient synthesis of 1, 2, 4- triazine derivatives is described by the condensation of substituted 4-(2-chloro-quinoline-3yl methylene)-2-[phenyl-4H-oxazol-5-one and phenyl hydrazine an equimolar sodium acetate and acetic acid as a solvent. The newly synthesized compounds were evaluated for their antimicrobial activity.