Lagerstroemia speciosa is locally known as jarul in Bangladesh. Nearly each part of Lagerstroemia speciosa possess diverse considerable biological function. Leaves avail anti-diabetic, antiulcer, antipyretic, analgesic, purgative, stimulant etc characteristics. Therefore the aim of the present study is to investigate Anti-diarrhoeal activity of ethanolic extract of Lagerstroemia speciosa leaves. Anti-diarrhoeal activity of leaves extract was evaluated using castor oil induced and magnesium sulphate induced method at 250 mg/kg and 350 mg/kg dose and compared with standard drug Loperamide at 3 mg/kg dose. Leaves extract of Lagerstroemia speciosa showed significant anti-diarrhoeal activity. In case of castor oil induced method, % inhibition of defaecation were 40% and 53.33% at the dose of 250 mg/kg and 350 mg/kg respectively and 60% inhibition was obtained at 3 mg/kg dose of Loperamide standard drug. In case of magnesium sulphate induced method, % inhibition were 41.67% and 58.33% at the dose of 250 mg/kg and 350 mg/kg respectively and 75% at the dose of 3 mg/kg of Loperamide. Lagerstroemia speciosa showed significant Anti-diarrhoeal activity and the present study supports the use of this plant parts to be used traditionally to treat diarrhoea.
