Herbal medicines have been broadly consumed since ancient times and the clinically proven by some researches regarding their advantageous have been realized by patients for their better therapeutic values with less toxic and adverse effects compared to contemporary or synthetic medicines. The active components inside the herbs are highly water soluble, but low absorption due to hardness to cross lipid membrane, huge molecular size, thus resulting into low bioavailability and efficacy. Phytotherapeutics need high scientific approach to deliver the active constituents in a sustained manner to achieve patients’ compliance and cure diseases more safe and efficiently. Combining herbal medicine with nanotechnology is the best approach due to the nanostructuted system might be able to increase efficacy of plant extracts, reducing dose, toxicity, and side effects. Herbal drugs encapsulated with nanocarriers might be used at a sufficient concentration during the whole treatment process, and directing into the target site to give effective therapeutic effects. Thus, the aim of this study is to review nanocarriers used in herbal drugs delivery system.