This research is a casual-comparative one in type, where we have made effort to study and compare the general health conditions of Iranian universities' active and inactive academic staff. Samples included 250 members of academic staff of Iranian universities selected randomly and compared as two active and inactive groups. General Health Questionnaire 28 was applied as a means of research, validity and reliability has been reported in different research works mentioned. Women in this research were found to enjoy better health; the same was the case with the married academic members. In respect of last educational degree and academic rank, it was understood that, junior instructor bachelors were of better general health condition compared to others. Review of physical activity showed 193 samples were physically active and 51 of them inactive.