Scholars Research Library

Scholars Research Library

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Der Pharmacia Lettre

Abstract

Conventional and microwave assisted synthesis of novel pyrimidine derivatives as antimicrobial and antitubercular agent

Author(s): Dipen K. Sureja, Sandip P. Dholakia and Kantilal R. Vadalia

A simple and efficient approach towards single step synthesis of 6-amino-5-cyano-2-(hydroxy/mercapto)-4- substitutedpyrimidine derivatives has been developed by three component condensation of aromatic aldehydes, malononitrile and urea or thiourea using conventional heating and microwave irradiation technique. Some of these novel derivatives showed moderate to potent in-vitro antibacterial, antifungal and antitubercular activity.


javgrown.com scatvids.club javvids.com