Two new simple, sensitive and economical visible spectrophotometric methods were described for the estimation of pramipexole dihydrochloride in pure and dosage forms. This method is based on the diazocoupling reactions between the drug and pluroglucinol (Method –A) and resorcinol (Method –B). The colored products exhibited an absorption maximum at 520 nm (Method –A) and 600 nm (Method –B). Beer’s law obeyed in the concentration range of 4.0-20 μg/ml, (Method –A) and 2.0-10 μg/ml (Method –B).The results obtained by the proposed method were in good agreement with the labeled amounts. The proposed methods offer the advantages of rapidity, simplicity, sensitivity and normal cost and can be easily applied to resource-poor settings without the need for expensive instrumentation and reagents.
