Cancer cervix is a very common disease in Indian women, especially in the multiparous, and in the older age group women mostly belonging to the low socio economic group. This study was conducted to determine the importance of the Papanicolaou (Pap) smears for the diagnosis of Pre- malignant and malignant lesions of the cervix. Pap smears of 300 women who attended the Gynaec Out patient Department at Shadan Institute Of Medical Sciences and Post Graduate Medical Centre, Hyderabad, were examined. In this study 156 (52%) had normal smears, 109 (36.33%) showed inflammatory changes , and 35 (11.67%) showed Premalignant or Malignant changes. The Pap smear examination is an useful test to diagnose neoplastic lesions of the cervix.