Chrozophora prostrata (Family- Euphorbiaceae), it is an herbaceous perennial plant, is found throughout Egypt, Palestine, Syria, Western Arabia, tropical Africa from Senegal to Ethiopia, South Africa (Transvaal) and tropical Asia and it is the most important herb in ayurvedic medicine. The herb has been highly valued for its traditional use as blood purifier which is also used for the treatment of chronic persistent fever, syphilis, gonorrhea, leucoderma as well as its antioxidant properties helps to maintain cell integrity. In the present study of phytochemical screening and in vitro antioxidant activities of the whole plant extract of Chrozophora prostrata (Suryavarta, Neel kanthi, Shad, Khudi okra) was evaluated. For phytochemical screening, some common standard tests those are available for phytochemical screenings were done. In vitro antioxidant activities of the whole plant extract of Chrozophora prostrata was performed using cupric reducing antioxidant capacity, DPPH free radical scavenging assay, total phenol content, total flavonoid content, total antioxidant capacity, nitric oxide scavenging and scavenging of hydrogen peroxide assays.