Fever is an important very prevalent disease in children. Fever is developed in the body during response to releasing internal pyrogenic agents throughout infections, malignancy, and inflammatory and rheumatic processes as well as external pyrogenic agents including microbes and toxins. In Iran, medicinal plants have long been used to treat diseases, and fever have been commonly treated with medicinal plants, as well. Therefore, this review article sought to report the medicinal plants used to treat fever in children. In this study, the key words including fever, children, medicinal plants, traditional medicine, and Iran were used to search in the databases Web of Science, PubMed, Scopus, International Science Citation Center, and Magiran, and the articles of interest were retrieved. The medicinal plants Matricaria recutita, Achilleamil lefolium, Sambucus nigra, Tilia cordata, Hyssopus officinalis, Allium sativum, Lavandula officinalis, and Mentha piperita were reported to have refrigerant properties. The antipyretic medicinal plants in the present study could relieve the intensity of fever in children and play a refrigerant role by means of the effective substances with antioxidant, antimicrobial, and anti-inflammatory properties through eliminating the involved factors of fever happening.