Scholars Research Library

Scholars Research Library

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Der Pharmacia Lettre

Abstract

New first derivative UV spectrophotometric determination method for lornoxicam in pharmaceutical formulations.

Author(s): Santosh R. Karajgi, Shahid M. Gaffar and Ramaling B. Kotnal

A simple, novel, sensitive, and specific First derivative uv spectrophotometric method was developed and validated for the determination of Lornoxicam in bulk and its dosage form. The drug was estimated by using 0.01 N NaOH as solvent for this study, which is determined by spectrophotometrically at 377 nm absorption maximum. Beer’s law obeyed in the concentration range of 10-50μg/ml. The recovery studies ascertained the accuracy of the proposed method and results were validated as per ICH guidelines. The results were found satisfactory and reproducible.


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