Scholars Research Library

Scholars Research Library

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Der Pharmacia Lettre


New first derivative UV spectrophotometric determination method for lornoxicam in pharmaceutical formulations.

Author(s): Santosh R. Karajgi, Shahid M. Gaffar and Ramaling B. Kotnal

A simple, novel, sensitive, and specific First derivative uv spectrophotometric method was developed and validated for the determination of Lornoxicam in bulk and its dosage form. The drug was estimated by using 0.01 N NaOH as solvent for this study, which is determined by spectrophotometrically at 377 nm absorption maximum. Beer’s law obeyed in the concentration range of 10-50μg/ml. The recovery studies ascertained the accuracy of the proposed method and results were validated as per ICH guidelines. The results were found satisfactory and reproducible.