This inquiry demonstrates the therapeutic plant sources that are often used against various aetiological operators and have recently been incorporated into several pharmaceutical goods. Azadirachta indica, Ocimum gratissimum, Jatropha spp, and Carica papaya were among the plant sources used in this study. Candida species, Rhizopus spp, Rhizomucor spp, Mucor spp, Aspergillus spp, and Penicillium spp were among the parasitic species isolated from maritime sources throughout the study. Parasitic organisms such as Candida spp., Rhizopus spp., and Mucor spp. were shown to be essential to the three types of water sources used: fast moving water, slow water, and stale well water. Plant flotsam and jetsam sullying from other ecological sources, such as soil, might explain the presence of parasite species in the studied water sources. The antimycotic capabilities of these plant isolates were determined by the antifungal activity of these sources, which revealed their potency against the majority of infectious isolates with varying degrees of growth restraint. Out of the four plant sources tested, the extract from A. indica was shown to be the most active, with a hindrance zone more than 15mm and total growth restraint in certain cases against parasite secludes, while the extract from C. papaya separates had the least effect. This means that the dynamic therapeutic plant source may be improved for future antimycotic therapy in disease control, and it may be able to address some antimicrobial blockage concerns that are caused by things from a normal beginning point.