Background: Ultraviolet (UV) radiation is part of the electromagnetic spectrum longer than x-rays but shorter than that of visible light wavelength between 100 and 400 nm. Objective: This work aimed to investigate the biological effect of UVA on rat heart tissue as blood cell count, heart enzyme, trace elements content and histopathological changes.
Materials and Methods: The heart samples were selected from 40 Wister male rats. They were divided into equal four groups (ten for each) as; the control group, which is not exposed to any radiation, while the other three groups were exposed to different UVA-radiation doses for continuous doses (group II (500.00 J/cm2), group III( 793.15 J/cm2) and group IV (1733.18 J/cm2)). The study was examined some trace elements by Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP-OES). Heart enzyme of the blood serum was used spectrophotometer, and CBCs were used mindary hematology analyzer Bc 2800, the histopathological changes of heart tissue examined by Light Microscope (LM) and Transmission Electron Microscope (TEM) examined myocardial cells.
Results: The present work revealed increase of trace elements concentrations of (Ca, Cr, Cu, Fe, K, Mg, Na, Zn), mild changes of the complete blood picture (RBC, WBC, PLT and Hb) and heart enzyme, A mild to marked histopathological changes on the heart tissue. The fine ultra-structure revealed destructive myofibrile and increased of microsomes structure and lysosome vesicles. There are statistical significant decrease of mitochondria surface area and thickness of z-band of myocytes. It could be concluded that the continuously exposed to the UVA at long time caused a harmful in the heart tissues with a potential unbeneficial role of the UVA radiation exposed, so it must be used protection agent to avoid the harmful ionize radiation affected from the UVA radiation from the long-time exposed to sunlight.