Smoking Habit and Telomere Length Relationship in Minangkabau Ethnicity Males | Abstract
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Smoking Habit and Telomere Length Relationship in Minangkabau Ethnicity Males

Author(s): Afriwardi, Delmi Sulastri, Yuniar Lestari

Introduction: Smoking habit is one of major health-related social problem in Indonesia. It is predicted that smoking could accelerate individual ageing based on procuring oxidative stress. Toxic components within cigarette smoke act as exogenous exposure which is responsible for increasing Reactive Oxygen Species (ROS) that lead to telomere shortening. The aim of this research is to know the relationship between Smoking habit and telomere length in Minangkabau ethnicity males Method: This cross-sectional study included 130 males, Minangkabau ethnicity, ages 30-40-year-old. The characteristics and smoking habit data were collected by using questionnaire, while the blood was taken to measure telomere length by using O’Callaghan & Fenech. The data was analyzed by Student’s T test, One Way- Anova and correlation’s test. The result: This research indicates that the mean length of telomeres was 579,75 + 314,75 %. The average length of smoked cigarettes was 14,96+13,67 years and types of cigarette the most widely used is filter cigarettes as 64%. The average length of the telomere subject does not smoke are 638,07 + 380,11 bp, smoking filter cigarettes 582,74 + 279,83 bp and smoking non-filter cigarettes as516,32 + 241,13 bp. There was a significant negative correlation between length of smoked with telomere length (r = -206, p=04). There was the average difference of smokers with no smokers (p=0.03). Conclusion: The longer smoke, the shorter the telomeres and telomere length smoking non-filter cigarettes has shorter than non-smokers and smoking filter cigarettes