Verbena officinalis Linn, the common vervain or common verbena, is a perennial herb native to Europe. It grows up to a meter high, with an upright habitus. The lobed leaves are toothed, the delicate spikes hold mauve flowers. This plant prefers limey soils .The aim of this study was to overview its therapeutic effects than its nutritive and industrial effects. This review article was carried out by searching studies in PubMed, Medline, Web of Science, and Iran Medex databases .The initial search strategy identified about 128 references. In this study, 113 studies was accepted for further screening and met all our inclusion criteria [in English, full text, therapeutic effects of Verbena officinalis Linn and dated mainly from the year 1964 to 2015.The search terms were “Verbena officinalis Linn.”, lemon balm, “therapeutic properties”, “pharmacological effects”. It is commonly used for ameliorative effect, antitumor, pharmacokinetic effect. antioxidant and antifungal activity, antiradical efficacy, analgesic activity, neuroprotective effects, anti-inflammatory activity, inflammatory, wound healing, anti-trypanosomacruzi activity, antinociceptive and antioxidant activities, antioxidant/anti -inflammatory ,anti-rhinosinusitis, biological activity, anti-skin infection.Verbena officinalis Linn. Possess very therapeutic effects. Nevertheless, it is still required to carry out more studies on this plant to identify its other properties.