Scholars Research Library

Scholars Research Library

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Der Pharmacia Lettre


Synthesis and antibacterial activity of 5-chloro-N-cyclohexyl- 6-thio substituted-nicotinamide derivatives

Author(s): P. V. Maske and S. J. Makhija

A new route for the synthesis of 5-chloro-N-cyclohexyl-6-thio substituted-nicotinamide derivatives is reported. The antibacterial activity of all the synthesized compounds (4a-h) has been performed against gram positive and gram-negative bacteria. The compound 4c has found excellent antibacterial activity. The newly synthesized compounds are characterized by spectral data.