A novel five-membered N-glucosylated 1, 3, 4-thiadiazolidines (7a-f) have been synthesized by the interaction of substituted N-arylidine thiocarbohydrazides (4) with N-tetra-O-acetyl-β-D-glucopyranosyl isocyanodichloride (5). The later requisite was synthesized by excessive chlorination of N-tetra-O-acetyl-β-D-glucopyranosyl isothiocyanate. The structure of all the newly synthesized 2-tetra-O-acetyl-β-D-glucopyranosylimino-5-(arylidinehydrazino)-1,3,4-thiadiazolidines (7a-h) were established on the basis of usual chemical characteristics, IR, 1H NMR, 13C NMR and mass spectral analyses.
