Scholars Research Library

Scholars Research Library

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Der Pharmacia Lettre


Synthesis and studies on antibacterial activity of some new chalcones and flavones containing naphthyl moiety

Author(s): Sainath B. Zangade, Archana Y. Vibhute, Shivaji B. Chavan and Yeshwant B. Vibhute

A series of 2-Hydroxychalcones were synthesized from substituted 2-acetyl-1-naphthol / 2-acetyl- 1-naphthol and substituted benzaldehyde via Claisen-schmidt condensation. Further these chalcones converted into flavones by oxidative cyclisation of chalcones using DMSO/I2. The structures of synthetic compounds have been characterized by analytical and spectral data. All synthesized compounds have been evaluated for their antibacterial activity.