Der Pharmacia Lettre
Anees A. Siddiqi , Jaya Dwivedi, Swapnil Sharma, Rajani Chauhan
Present work describes the Synthesis of 3-(3-substituted-1H-indon-1-yl)-2-phenylquinoline-4-
carboxylic acid derivatives by Pfitzinger reaction of isatin with 2(1H-indol-1-yl)-1-phenyl
ethanone and 1-phenyl-2-[-3-(substituted)-1-H-indole-1-yl] ethanone. The structures of all the
compounds are established by elemental analysis, IR, 1H NMR and Mass spectral data. These
compounds possess excellent antimicrobial activity against bacteria and fungi.