Der Pharmacia Lettre
Shabista Khan, F.B.Bux, Arun Singh
The reaction between benzimidazole with N-[4-(2-chloroacetyl)phenyl]acetamide affords N-[4-
(2-(1H-benzimidazol-1-yl) acetyl] phenyl acetamide,which upon hydrolysis yield 1-(4-
aminophenyl)-2-(1H-benzimidazol-1-yl)ethanone. The Diazotion of 1-(4-aminophenyl)-2-(1Hbenzimidazol-
1-yl)ethanone couple with salicylic acid,they afford the ligand compound and
named as 5-([4-(2-(1H-benzimidazol-1-yl)acetyl)phenyl]diazenyl)-2-hydroxybenzoic acid(SABI).
The transition metal complexes of Cu2+, Co2+ ,Ni2+, Mn2+ and Zn2+ of SA-BI have been
prepared and characterized by elemental analyses, spectral studies, magnetic moment
determination, molar conductivity measurement and microbicidal activity.