Der Pharmacia Lettre
Vanita A Navale, S.B. Zangade, R.S. Shinde, S.G. Patil
New chalcones (3a-k) were synthesized from substituted 2-hydroxy acetophenones and 2-
benzyloxy, 3-benzyloxy-4-methoxy, 4-benzyloxy-3-methoxy benzaldehyde via claisen-schmidt
condensation. Further these chalcones converted into corresponding flavones (4a-k) by oxidative
cyclization of chalcones using DMSO-I2. The structure of synthesized compound was confirmed
by elemental analysis and spectral data. The newly synthesized compounds were screened for
antimicrobial activity against E-coli, S. Typhi, Staph. aureus, and Aspergillus niger.