Quantitative information regarding effects of micronutrients such as Boron, Zinc and Copper in wheat (Triticum aestivum) is scarce. Foliar application can guarantee the availability of nutrients to crops for obtaining higher yield. So to study the response of wheat to foliar application of these micronutrients, tow experiments were a factorial on randomized complete block design with four replications conducted at Chenaran and Mashhad, Iran during 2010-11. Treatments of these experiments were Type of elements (Zinc, Boron and Copper) Doses of Foliar application (0, 1 and 2 lit/ha) and Varieties (Gaskojen and Pishtaz). The experiments were conducted under wellwatered conditions. Type of elements was significant on the number of spikes per plant, Grain per spike, Grain in square meter, Harvest Index (HI%) and Grain yield (kg/ha) but had no effect on thousand grain weigh. Boron and Zinc showed higher amounts in mentioned traits than Copper, although Boron in Chenaran, and Zinc in Mashhad were more effective. the number of spikes per plant, Grain in square meter, and Grain yield increased with raising in Doses of foliar application, so that highest of these were in dose of 2lit/ha. Varieties and locations resulted different in evaluated traits generally. Chenaran was better than Mashhad, and Gaskojen than Pishtaz in Yield and yield components. The findings found at this study can be used in management recommendations of wheat. Further, it is recommended that more attention should be paid to Zn and B nutrition in mentioned locations.