Most people opt to use natural and traditional methods instead of chemical drugs and intrusive methods of modern medicine to treat minor illnesses and disorders of children or newborns. Since gastrointestinal, infectious, and respiratory diseases are the most significant diseases in children, this review article sought to identify and report the native medicinal plants of Iran which have been used to treat gastrointestinal disorders in children. For this study, the key words consisting of digestion, children, medicinal plants, traditional medicine, and Iran were used to search in Web of Science, PubMed, Scopus, Islamic Science Citation Center, and Magiran and relevant articles were selected. The findings indicated that in Iran, nine medicinal plants, Foeniculum vulgaris, Pimpinella anisum, Acorus calamus, Anethum graveolens, Zingiber officinalis, Lavandula officinalis, Capiscum minimum, Mentha piperita, and Carum carvi are used to treat gastrointestinal disorders in children. These plants contain phenolic and antioxidant compounds, which could be used to prevent and treat bloat, colic, and anorexia.