All around the world Entada africana is used traditionally/folk to treat several diseases, as a source of gum, insecticides, food and in some carpentry works. Several studies explored pharmacological and ethno botanical aspects of this plant and isolate various phytochemicals which are responsible for its anti-inflammatory, analgesic, antibacterial, antioxidant, antiviral, anti-angiogenic, cytotoxic properties. Sugars, triterpenes, flavonoids and saponins are mainly responsible for the abovementioned pharmacological activities. However, some more research is required to identify other phytochemical constituents which can be used to cure other ailments.