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VKK Mandlem

Department of Pharmacology, CMR College of Pharmacy, Hyderabad, India

Publications

  • Research   
    Dulaglutide Improves Aluminum Chloride Induced Cognitive Dysfunction in Diabetes Associated Alzheimer’s Rat Model
    Author(s): VKK Mandlem*, Vazra Sravani K, GSN Koteswara Rao, Ravi Manne and Ramoji Kosuru

    Background: Type-2 diabetes is an etiological factor for Alzheimer’s. GLP-1 analogues were prescribed in treating type-2 diabetes mellitus, where the presence of GLP-1 receptors in brain also makes it a potential target for Alzheimer’s disease. Aim: The aim of the study is to evaluate the neuroprotective effect of dulaglutide in aluminum chloride induced cognitive dysfunction in type-2 diabetes associated Alzheimer’s experimental rats by conducting behavioral studies, estimating the biochemical parameters and histopathological changes involved in the pathogenesis of the disease. Objective: To evaluate the effect of GLP-1 analogue on learning and memory in Aluminum chloride induced Alzheimer’s disease in type-2 diabetic rats by using physical and biochemical methods. Methods.. Read More»
    DOI: 10.4172/ 0976-1233.004

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Awards & Nominations

Google Scholar citation report
Citations : 21330

Annals of Biological Research received 21330 citations as per Google Scholar report

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