Nanotechnology is the most promising field for generating new applications in medical field. Silver ion has been used for centuries to prevent and treat variety of diseases and infections. In this study we have selected Polyvinyl pyrrolidine (PVP) as a binder for nano silver particles. This was done with the aim to investigate the blend behavior of PVP with nanoparticles which can have their application in medical field. PVP is a water soluble polymer with a large number of consumer uses. This commercial success derives from its biological compatibility, low toxicity, film-forming and adhesive characteristics, unusual complexing ability, relatively inert behavior toward salts and acids, and its resistance to thermal degradation in solution. Because of these diverse properties, FTIR and 13C NMR are employed successfully to study the blend behavior of PVP with nanosilver. FTIR spectrum is recorded in the range 400-4000cm-1. The characteristic vinyl bands are observed in the region 965 cm-1and C-C, C=O stretching and bending are found in the appropriate region in pure PVP and PVP and Nano silver complex . The 13C NMR provides valuable information about the structure of the complex. FTIR and NMR studies confirm that structure of the complex is stable and the characteristic bands of PVP are not disturbed by the presence of silver ions. Thus this study suggest that a product made of PVP and nanosilver composite can be used as external formulation such as wound healing in medical field.