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5-Hydroxy vasentine, a new pyrroloquinazoline alkaloids from Anisotes trisulcus (Forssk.) Nees | Abstract
Scholars Research Library

Scholars Research Library

Journal of Natural Product and Plant Resources

Abstract

5-Hydroxy vasentine, a new pyrroloquinazoline alkaloids from Anisotes trisulcus (Forssk.) Nees

Author(s): Mohamed A. El-Shanawany, Hanaa M. Sayed, Sabrin R.M. Ibrahim*and Marwa A. A. Fayed

5-Hydroxy vasentine (1), a new pyrroloquinazoline alkaloids, along with two known compounds: 7-hydroxy vasicine (2) and 7-hydroxy vasicinone (3), were isolated from the aerial parts of Anisotes trisulcus (Forssk.) Nees (Acanthaceae). Their structures were established by UV, IR, 1D and 2D NMR, in addition to mass spectroscopic data and comparison with literature data. The different fractions were evaluated for their cytotoxic activity using the brine shrimp bioassay.


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