Cytotoxic Effects of Tabebuia Rosea Oils (Leaf and Stem Bark) | Abstract
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Cytotoxic Effects of Tabebuia Rosea Oils (Leaf and Stem Bark)

Author(s): G.K. Oloyede, I.A. Oladosu, A. F. Shodia, O.O. Oloyade

The leaf and stembark of Tabebuia Rosea were separately collected, dried and grounded. The powdered samples were subjected to distillation using a hydro-distiller (all-glass clevenger apparatus), to extract the essential oil present in the plant samples. GC and GC/MS analysis were carried out on the essential oils and were found to contain a total of five and six compounds in the leaf and stembark respectively. The leaf contained o-xylene (2.13%), 2,4- dimethylhexane (1.03%), methyl cyclohexane (53.13%), methyl benzene (12.75%), 3-Pentene-2- one(0.11%) representing 69.15% of the total essential oil while the stem bark contained n-amyl ketone (46.69%), methyl cyclohexane (24.07%), methyl benzene (13.88%), α –carene (0.46%), β- carene (0.46%),and γ-carene (0.46%) representing 85.62% of the total essential oil. The toxicity of these oils was shown by brine shrimp test. The LC50 value (μg/ml) of 1.701 with upper confidence limit and lower confidence limit of 2.137 and 0.4678 respectively for both the leaf and stem bark indicated that the oils were highly toxic.