Method describes an HPTLC method for the simultaneous determination of Telmisartan and Amlodipine Besylate from tablet dosage form. This employes a precoated silica gel 60 F254 (0.2 mm thickness) on aluminium sheets and a mobile phase Ethyl acetate: 1, 4 Dioxane: Methanol: 25% Ammonia in the ratio of 15:1.5:3:1.5 v/v, having chamber saturation for 30 min at room temperature. The developing chamber was run upto 8cm. The Rf values was found to be 0.16 and 0.33 for Telmisartan and Amlodipine respectively. The plate was scanned and quantified at 323nm. The linear detector response was observed between 100 μg/ml to 500 μg/ml and 200 μg/ml to 1000 μg/ml for Telmisartan and Amlodipine respectively. The method so developed was validated for its accuracy and precision. The LOD and LOQ were found to be 0.025, 0.0747μg/ml and 0.0236, 0.0714μg/ml, respectively for Telmisartan and Amlodipine. The recovery was carried out by standard addition method. The Average recovery was found to be 100.38% and 100.24% for Telmisartan and Amlodipine respectively.