Ecological supportability is an undeniably significant issue in industry. As a harmless to the ecosystem and manageable way, developing microbial cell plants to create a wide range of important items has drawn in increasingly more consideration. During the time spent building microbial cell manufacturing plants, frameworks science assumes a critical part. This audit sums up the new uses of frameworks science in the plan and development of microbial cell production lines according to four points of view, including utilitarian qualities/proteins disclosure, bottleneck pathways distinguishing proof, strains resilience improvement and plan and development of manufactured microbial consortia. Frameworks science devices can be utilized to recognize utilitarian qualities/compounds engaged with the biosynthetic pathways of items. These found qualities are acquainted into proper suspension strains with construct designing microorganisms equipped for delivering items. In this way, frameworks science devices are utilized to distinguish bottleneck pathways, further develop strains resistance and guide plan and development of manufactured microbial consortia, bringing about expanding the yield of designed strains and building microbial cell production lines effectively.