Research Article
Synthesis and Evaluation for Anti-Infective Activities of 2-Arylidene-1-(4-Methyl-6- Phenylpyrimidin-2-YL) Hydrazides
Author(s): Simran Gupta*, Rahul Sharma and Prabodh Chander Sharma
Hydrazones constitute chemical entities, which are a vivid area of pharmaceutical, and drug candidates and spacious impedance as outstanding precursors for the discovery of numerous heterocyclic compounds. In addition, hydrazones pharmacophores are associated with profound biological activities, such as antimicrobial, antifungal, anthelmintic and antimalarial activity. The biological significance of benzaldehyde along with the pharmacological importance of hydrazine motivated us to synthesize some new benzaldehyde derivatives using pyrimidine as a starting material. In the present investigation, we describe the synthesis and anthelmintic, antibacterial, antifungal, and antimalarial evaluation of novel derivatives of selected drugs. The target compounds were synthesized taking pyrimidine as a starting material the yields of different synthesized compounds were found to be under differe.. Read More»
DOI:
10.37532/0975-5071.2025.17.01
